The victim, who is in her 20s, had spent the evening at a bar in Stockwell on Friday, July 31 last year before leaving the venue at around 2am.
She left the bar with four males, who she had befriended that night, and the group walked to nearby Slade Gardens where they shared alcohol and socialised.
The victim lost consciousness just half an hour later, and it is believed this is when the sexual assault took place.
The woman later awoke and found the men had left the park, and her bank cards were missing.
According to the Metropolitan Police, the four men were in a group together and are believed to be friends.
Detective Constable Colette Daoud, from the Met’s Central South Safeguarding team, said: “This was an atrocious attack on a lone woman who was targeted late at night and subjected to serious sexual violence.
“We are requesting the public’s help to identify the men pictured. If you recognise any of these men, please come forward and speak to us.
“If you have any information, no matter how insignificant it may seem, it is vital you get in touch.”
Anyone with information or who recognises the men captured in the CCTV is asked to contact police on 101, quoting reference CAD 4055/01AUG20, or via Crimestoppers anonymously on 0800 555 111.
In August 2020, three men, aged 45, 46 and 33, were arrested on suspicion of rape.
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This is in relation to a linked incident against the same victim in the early hours of Saturday, 1 August 2020.
They have since been released under investigation.